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Symbol
Name
ID
Pik3ca
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
MGI:1206581
Phenotype annotations related to homeostasis/metabolism
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Increased level of L-fucose in urine
Disease(s) Associated with PIK3CA
stomach cancer

Mouse Phenotypes
homeostasis/metabolism phenotype
abnormal circulating androgen level
increased circulating testosterone level
decreased circulating luteinizing hormone level
increased circulating insulin level
increased circulating leptin level
chylous ascites
impaired glucose tolerance
insulin resistance
abnormal hormone level
decreased incidence of tumors by chemical induction
Availability Mouse Genotype
Pik3catm1Jdo/Pik3catm1Jdo
Pik3catm1Bvan/Pik3ca+
Pik3catm1.1Rzl/Pik3catm1.1Rzl
Tg(Fabp4-cre)1Blw/0  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory