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Symbol
Name
ID
Stat1
signal transducer and activator of transcription 1
MGI:103063
Phenotype annotations related to homeostasis/metabolism
Darker colors indicate more annotations
Human Phenotypes
Type I diabetes mellitus
Medial calcification of large arteries
Disease(s) Associated with STAT1
immunodeficiency 31C

Mouse Phenotypes
increased myocardial infarct size
decreased susceptibility to neuronal excitotoxicity
increased macrophage nitric oxide production
decreased circulating interferon-gamma level
increased circulating interferon-gamma level
increased circulating interleukin-12b level
decreased circulating alkaline phosphatase level
pulmonary edema
abnormal nitric oxide homeostasis
Availability Mouse Genotype
Stat1tm1Dlv/Stat1tm1Dlv
Stat1tm1Rds/Stat1tm1Rds
Stat1tm1Uvin/Stat1tm1Uvin
Stat1tm2b(EUCOMM)Wtsi/Stat1tm2b(EUCOMM)Wtsi

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory