Symbol Name ID |
Cbfb
core binding factor beta MGI:99851 |
Darker colors indicate more annotations |
Mouse Phenotypes | abnormal megakaryocyte differentiation |
abnormal embryonic hematopoiesis |
abnormal thymus morphology |
abnormal thymus cell ratio |
small thymus |
thymus hypoplasia |
decreased thymocyte number |
enlarged spleen |
abnormal definitive hematopoiesis |
abnormal common myeloid progenitor cell morphology |
abnormal erythropoiesis |
abnormal T cell differentiation |
abnormal CD4-positive T cell differentiation |
abnormal T-helper 1 cell differentiation |
abnormal CD8-positive, alpha-beta T cell differentiation |
abnormal double-positive T cell morphology |
decreased double-positive T cell number |
increased double-positive T cell number |
abnormal myelopoiesis |
extramedullary hematopoiesis |
anemia |
impaired hematopoiesis |
abnormal megakaryocyte morphology |
increased erythroid progenitor cell number |
abnormal myeloblast morphology/development |
decreased erythroblast number |
thrombocytopenia |
increased CD4-positive, alpha-beta T cell number |
abnormal CD8-positive, alpha-beta T cell number |
decreased CD8-positive, alpha-beta T cell number |
absent T cells |
decreased lymphocyte cell number |
increased leukocyte cell number |
increased hematopoietic stem cell number |
abnormal CD8-positive, alpha beta T cell morphology |
abnormal spleen morphology |
small spleen |
spleen hypoplasia |
abnormal splenic cell ratio |
increased IgA level |
increased IgE level |
increased IgG1 level |
increased immunoglobulin level |
|
Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||||||||||
Cbfbtm1Spe/Cbfbtm1Spe Tg(Tek-GFP/Cbfb)1Spe/0 |
||||||||||||||||||||||||||||||||||||||||||||
Cbfbtm1Spe/Cbfbtm1Spe Tg(Tek-GFP/Cbfb)2Spe/0 |
||||||||||||||||||||||||||||||||||||||||||||
Cbfbtm1Spe/Cbfbtm1Spe | ||||||||||||||||||||||||||||||||||||||||||||
Cbfbtm1Tno/Cbfbtm1Tno | ||||||||||||||||||||||||||||||||||||||||||||
Cbfbtm1Tok/Cbfbtm1Tok | ||||||||||||||||||||||||||||||||||||||||||||
Cbfbtm1Tok/Cbfbtm1Tok Tg(Gata1-Cbfb)1Tok/0 |
||||||||||||||||||||||||||||||||||||||||||||
Cbfbtm2.1Spe/Cbfbtm2.1Spe | ||||||||||||||||||||||||||||||||||||||||||||
Cbfbtm1Ppl/Cbfb+ | ||||||||||||||||||||||||||||||||||||||||||||
Cbfbtm1Spe/Cbfbtm2.1Spe | ||||||||||||||||||||||||||||||||||||||||||||
Cbfbtm1Itan/Cbfbtm1Itan Tg(Lck-cre)1Cwi/0 (conditional) |
||||||||||||||||||||||||||||||||||||||||||||
Cbfbtm1Itan/Cbfbtm1Itan Tg(Cd4-cre)1Cwi/0 (conditional) |
||||||||||||||||||||||||||||||||||||||||||||
Cbfbtm1Lhc/Cbfbtm1Lhc Tg(Mx1-cre)1Cgn/0 (conditional) |
||||||||||||||||||||||||||||||||||||||||||||
Cbfbtm1Lhc/Cbfb+ Tg(EIIa-cre)C5379Lmgd/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 05/28/2024 MGI 6.13 |
|
|