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Symbol Name ID |
Prdm1
PR domain containing 1, with ZNF domain MGI:99655 |
| Darker colors indicate more annotations |
| Mouse Phenotypes | abnormal B cell differentiation |
abnormal plasma cell differentiation |
abnormal T follicular helper cell differentiation |
increased germinal center B cell number |
decreased plasma cell number |
absent plasma cells |
abnormal memory B cell number |
increased T follicular helper cell number |
abnormal plasma cell morphology |
increased spleen germinal center number |
increased spleen germinal center size |
increased splenocyte number |
abnormal germinal center B cell physiology |
decreased IgG level |
increased IgG level |
decreased IgM level |
decreased immunoglobulin level |
increased immunoglobulin level |
abnormal CD4-positive, alpha-beta T cell physiology |
abnormal splenocyte physiology |
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| Availability | Mouse Genotype | ||||||||||||||||||||
| Prdm1tm1.1Liz/Prdm1tm1.1Liz | |||||||||||||||||||||
| Cd19tm1(cre)Cgn/Cd19+ Prdm1tm1Clme/Prdm1tm1Clme (conditional) |
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| Prdm1tm1Clme/Prdm1tm1Clme Tg(Itgax-cre)1-1Reiz/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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