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Symbol
Name
ID

Tap2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
MGI:98484

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Human Phenotypes	Hemolytic anemia	Leukopenia	Thrombocytopenia	Elevated erythrocyte sedimentation rate
Disease(s) Associated with TAP2	Hemolytic anemia	Leukopenia	Thrombocytopenia	Elevated erythrocyte sedimentation rate
rheumatoid arthritis
systemic lupus erythematosus

Mouse Phenotypes		decreased effector memory CD4-positive, alpha-beta T cell number	increased CD4-positive, alpha-beta T cell number	increased central memory CD8 positive, alpha-beta T cell number	decreased CD8-positive, naive alpha-beta T cell number	decreased CD8-positive, alpha-beta T cell number	absent CD8-positive, alpha-beta T cells	decreased NK T cell number	abnormal NK cell physiology	abnormal cytotoxic T cell physiology
Availability	Mouse Genotype		increased CD4-positive, alpha-beta T cell number		decreased CD8-positive, naive alpha-beta T cell number	decreased CD8-positive, alpha-beta T cell number	absent CD8-positive, alpha-beta T cells	decreased NK T cell number	abnormal NK cell physiology	abnormal cytotoxic T cell physiology
	Tap2^jas/Tap2^jas
	Tap2^m1Btlr/Tap2^m1Btlr
	Tap2^m2Btlr/Tap2^m2Btlr
	Tap2^m3Btlr/Tap2^m3Btlr
	Tap2^M4Btlr/Tap2^M4Btlr

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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