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Symbol
Name
ID
Rb1
RB transcriptional corepressor 1
MGI:97874
Phenotype annotations related to hematopoietic system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Vitreous hemorrhage
Leukemia
Lymphoma
Disease(s) Associated with RB1
retinoblastoma

Mouse Phenotypes
hematopoietic system phenotype
abnormal macrophage differentiation
abnormal definitive hematopoiesis
abnormal erythropoiesis
abnormal myelopoiesis
anemia
increased megakaryocyte cell number
abnormal erythrocyte morphology
decreased erythrocyte cell number
low mean erythrocyte cell number
increased nucleated erythrocyte cell number
abnormal macrophage morphology
Availability Mouse Genotype
Rb1tm1Brd/Rb1tm1Brd
Rb1tm1Dwg/Rb1tm1Dwg
Rb1tm1Mlh/Rb1tm1Mlh
Rb1tm1Tyj/Rb1tm1Tyj
Rb1tm1Tyj/Rb1tm1Tyj
Tg(Rb1)1Blg/0
Rb1tm2Mlh/Rb1tm2Mlh
Rb1tm1Dwg/Rb1tm1Tyj
Rb1tm3Tyj/Rb1tm3.1Tyj
Tg(Nes-cre)1Atp/0  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory