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Symbol
Name
ID
Prnp
prion protein
MGI:97769
Phenotype annotations related to hematopoietic system
Darker colors indicate more annotations

Mouse Phenotypes
thymus atrophy
thymus hypoplasia
decreased thymocyte number
decreased DN2 thymocyte number
decreased DN4 thymocyte number
increased DN3 thymocyte number
abnormal T cell differentiation
increased double-negative T cell number
decreased double-positive T cell number
decreased CD4-positive, alpha-beta T cell number
decreased CD8-positive, alpha-beta T cell number
increased CD8-positive, alpha-beta T cell number
increased gamma-delta T cell number
abnormal B cell morphology
microgliosis
Availability Mouse Genotype
Prnptm1Cwe/Prnptm1Cwe
Tg(Prnp)a20Cwe/0
Prnptm1Cwe/Prnptm1Cwe
Tg(Lck-Prnp)33Cwe/0
Prnptm1Cwe/Prnptm1Cwe
Tg(Prnp*S170N*N174T)1020Aag/0

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory