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Symbol
Name
ID
Il1b
interleukin 1 beta
MGI:96543
Phenotype annotations related to hematopoietic system
Darker colors indicate more annotations
Human Phenotypes
Increased circulating IgA level
Increased circulating IgE level
Increased circulating IgG level
Decreased circulating antibody level
Paraproteinemia
Epistaxis
Joint hemorrhage
Persistent bleeding after trauma
Bruising susceptibility
Purpura
Petechiae
Abnormal megakaryocyte morphology
Increased megakaryocyte colony forming unit count
Anemia
Hemolytic anemia
Anemia of inadequate production
Poikilocytosis
Acanthocytosis
Leukocytosis
Leukopenia
Thrombocytopenia
Congenital thrombocytopenia
Intermittent thrombocytopenia
Abnormal platelet shape
Abnormal platelet volume
Decreased mean platelet volume
Multiple myeloma
Splenomegaly
Hepatosplenomegaly
Disease(s) Associated with IL1B
cystic fibrosis
IgA glomerulonephritis
multiple myeloma
pancreatic cancer
systemic lupus erythematosus
thrombocytopenia

Mouse Phenotypes
abnormal lymphocyte physiology
abnormal macrophage physiology
Availability Mouse Genotype
Il1btm1Lvp/Il1btm1Lvp

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory