Symbol Name ID |
Hmox1
heme oxygenase 1 MGI:96163 |
Darker colors indicate more annotations |
Human Phenotypes | Bleeding with minor or no trauma |
Epistaxis |
Gingival bleeding |
Gastrointestinal hemorrhage |
Hematemesis |
Melena |
Intracranial hemorrhage |
Intraventricular hemorrhage |
Joint hemorrhage |
Muscle hemorrhage |
Oral cavity bleeding |
Persistent bleeding after trauma |
Bruising susceptibility |
Purpura |
Petechiae |
Spontaneous hematomas |
Thromboembolism |
Reduced factor VIII activity |
Prolonged partial thromboplastin time |
Splenic rupture |
Disease(s) Associated with HMOX1 | ||||||||||||||||||||
factor VIII deficiency |
Mouse Phenotypes | increased splenocyte proliferation |
enlarged spleen |
spleen hyperplasia |
extramedullary hematopoiesis |
anemia |
microcytic anemia |
decreased erythrocyte cell number |
decreased hematocrit |
decreased hemoglobin content |
decreased mean corpuscular volume |
anisocytosis |
increased granulocyte number |
abnormal leukocyte cell number |
increased B cell number |
increased CD4-positive, alpha-beta T cell number |
increased CD8-positive, alpha-beta T cell number |
decreased macrophage cell number |
increased macrophage cell number |
abnormal splenic cell ratio |
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Availability | Mouse Genotype | |||||||||||||||||||
Hmox1tm1.2Gkl/Hmox1tm1.2Gkl | ||||||||||||||||||||
Hmox1tm1Poss/Hmox1tm1Poss | ||||||||||||||||||||
Hmox1tm1.1Gkl/Hmox1tm1.1Gkl Lyz2tm1(cre)Ifo/Lyz2+ (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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