Symbol Name ID |
Ptpn6
protein tyrosine phosphatase, non-receptor type 6 MGI:96055 |
Darker colors indicate more annotations |
Mouse Phenotypes | decreased B cell proliferation |
increased splenocyte proliferation |
abnormal thymus morphology |
abnormal thymus development |
small thymus |
thymus atrophy |
decreased thymocyte number |
enlarged spleen |
decreased immature B cell number |
abnormal T cell differentiation |
abnormal CD8-positive, alpha-beta T cell differentiation |
increased erythroid progenitor cell number |
abnormal granulocyte morphology |
increased neutrophil cell number |
increased granulocyte number |
abnormal leukocyte cell number |
increased dendritic cell number |
decreased mature B cell number |
decreased B-1 B cell number |
decreased B-2 B cell number |
decreased follicular B cell number |
decreased marginal zone B cell number |
increased B-1 B cell number |
increased B-1a cell number |
increased B-1b cell number |
increased plasma cell number |
decreased B cell number |
increased B cell number |
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number |
increased effector memory CD4-positive, alpha-beta T cell number |
increased central memory CD8 positive, alpha-beta T cell number |
increased effector memory CD8-positive, alpha-beta T cell number |
increased CD8-positive, alpha-beta memory T cell number |
decreased CD8-positive, naive alpha-beta T cell number |
increased T cell number |
increased macrophage cell number |
increased monocyte cell number |
increased leukocyte cell number |
abnormal plasma cell morphology |
abnormal CD8-positive, alpha beta T cell morphology |
abnormal microglial cell morphology |
abnormal myeloid leukocyte morphology |
abnormal immunoglobulin level |
increased IgA level |
decreased IgD level |
increased IgG level |
decreased IgM level |
increased IgM level |
increased immunoglobulin level |
abnormal T cell physiology |
increased microglial cell activation |
abnormal bone marrow cell physiology |
|
Availability | Mouse Genotype | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Ptpn6em1.1Shoy/Ptpn6em1.1Shoy | |||||||||||||||||||||||||||||||||||||||||||||||||||||
Ptpn6m1Anu/Ptpn6m1Anu | |||||||||||||||||||||||||||||||||||||||||||||||||||||
Ptpn6m1Btlr/Ptpn6m1Btlr | |||||||||||||||||||||||||||||||||||||||||||||||||||||
Ptpn6m3Btlr/Ptpn6m3Btlr | |||||||||||||||||||||||||||||||||||||||||||||||||||||
Ptpn6m4Btlr/Ptpn6m4Btlr | |||||||||||||||||||||||||||||||||||||||||||||||||||||
Ptpn6M5Btlr/Ptpn6M5Btlr | |||||||||||||||||||||||||||||||||||||||||||||||||||||
Ptpn6m6Btlr/Ptpn6m6Btlr | |||||||||||||||||||||||||||||||||||||||||||||||||||||
Ptpn6m7Btlr/Ptpn6m7Btlr | |||||||||||||||||||||||||||||||||||||||||||||||||||||
Ptpn6me-B2/Ptpn6me-B2 | |||||||||||||||||||||||||||||||||||||||||||||||||||||
Ptpn6me-v/Ptpn6me-v | |||||||||||||||||||||||||||||||||||||||||||||||||||||
Ptpn6me/Ptpn6me | |||||||||||||||||||||||||||||||||||||||||||||||||||||
Ptpn6m3Btlr/Ptpn6+ | |||||||||||||||||||||||||||||||||||||||||||||||||||||
Cd19tm1(cre)Cgn/Cd19+ Ptpn6tm1Rsky/Ptpn6tm1Rsky (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 05/21/2024 MGI 6.23 |
|
|