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Symbol
Name
ID

Bcr
BCR activator of RhoGEF and GTPase
MGI:88141

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Human Phenotypes

Abnormality of blood and blood-forming tissues

Leukocytosis

Abnormal granulocyte morphology

Abnormal basophil morphology

Acute lymphoblastic leukemia

Ph-positive acute lymphoblastic leukemia

T-cell acute lymphoblastic leukemias

Chronic myelogenous leukemia

Myeloproliferative disorder

Thrombocytopenia

Thrombocytosis

Lymphoma

Splenomegaly

Disease(s) Associated with BCR

acute lymphoblastic leukemia

chronic myeloid leukemia

Mouse Phenotypes		abnormal definitive hematopoiesis	increased neutrophil cell number	increased leukocyte cell number	decreased hematopoietic stem cell number	abnormal neutrophil physiology	abnormal bone marrow cell physiology
Availability	Mouse Genotype	abnormal definitive hematopoiesis	increased neutrophil cell number	increased leukocyte cell number	decreased hematopoietic stem cell number	abnormal neutrophil physiology	abnormal bone marrow cell physiology
	Bcr^tm1Hkp/Bcr^tm1Hkp
	Bcr^{tm1(BCR/ABL)Tsr}/Bcr⁺
	Bcr^{tm1(BCR/ABL)Tsr}/Bcr⁺ Tg(Vav1-cre)#Cgp/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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