Symbol Name ID |
Apc
APC, WNT signaling pathway regulator MGI:88039 |
Darker colors indicate more annotations |
Human Phenotypes | Cerebellar hemorrhage |
Abnormal bone marrow cell morphology |
Hepatosplenomegaly |
Disease(s) Associated with APC | |||
medulloblastoma | |||
pancreatic cancer |
Mouse Phenotypes | abnormal thymus morphology |
abnormal Hassall's corpuscle morphology |
small thymus |
thymus hypoplasia |
decreased thymocyte number |
abnormal T cell differentiation |
increased double-negative T cell number |
arrested T cell differentiation |
anemia |
decreased hematocrit |
increased mast cell number |
decreased NK cell number |
decreased NK T cell number |
decreased T cell number |
decreased macrophage cell number |
abnormal effector T cell morphology |
decreased splenocyte number |
abnormal NK T cell physiology |
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Availability | Mouse Genotype | ||||||||||||||||||
ApcMin/Apc+ | |||||||||||||||||||
ApcMin/Apc+ Tg(Rorc-EGFP)1Ebe/? |
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Apctm1.1Alew/Apc+ | |||||||||||||||||||
Apctm1.1Rsmi/Apc+ | |||||||||||||||||||
Apctm1.1Tno/Apc+ | |||||||||||||||||||
Apctm1.1Tyj/Apc+ | |||||||||||||||||||
Apctm1Cip/Apc+ | |||||||||||||||||||
Apctm2.1Alew/Apc+ | |||||||||||||||||||
Apctm2.1Rak/Apc+ | |||||||||||||||||||
Apctm1Kk/Apctm1Kk Tg(Lck-cre)1Cwi/? (conditional) |
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Apctm2.1Cip/Apctm2.1Cip Tg(Ttr-cre/Esr1*)1Vco/0 (conditional) |
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Apctm2Rak/Apctm2Rak Tg(KRT14-cre)8Brn/0 (conditional) |
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Apctm2Rak/Apctm2Rak Tg(Car1-cre)5Flt/0 (conditional) |
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Apctm1Tno/Apc+ Tg(CDX2-cre)101Erf/0 (conditional) |
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Apctm1Tno/Apc+ Tg(Vil1-cre)997Gum/0 (conditional) |
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Apctm2Rak/Apc+ Tg(Car1-cre)5Flt/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/28/2024 MGI 6.13 |
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