Symbol
Name
ID

Mtor
mechanistic target of rapamycin kinase
MGI:1928394

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Mouse Phenotypes

decreased splenocyte apoptosis

decreased B cell proliferation

decreased T cell proliferation

decreased splenocyte proliferation

abnormal thymus cell ratio

decreased thymocyte number

abnormal B cell differentiation

decreased transitional stage T1 B cell number

abnormal T cell differentiation

decreased double-positive T cell number

increased mean corpuscular hemoglobin

decreased neutrophil cell number

decreased follicular B cell number

decreased marginal zone B cell number

decreased plasma cell number

decreased B cell number

abnormal T cell subpopulation ratio

decreased CD4-positive, alpha-beta T cell number

increased CD4-positive, alpha-beta T cell number

increased CD8-positive, alpha-beta T cell number

increased regulatory T cell number

decreased monocyte cell number

abnormal T cell morphology

small spleen

decreased splenocyte number

abnormal B cell physiology

decreased IgG level

decreased IgM level

abnormal T cell physiology

Availability

Mouse Genotype

Mtor^chino/Mtor^chino

Mtor^tm1Lgm/Mtor^tm1Lgm

Mtor^{tm1a(EUCOMM)Wtsi}/Mtor⁺

Mtor^tm1.2Koz/Mtor^tm1.2Koz
Tg(Cd4-cre)1Cwi/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/28/2024 MGI 6.13