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Symbol
Name
ID

Orai1
ORAI calcium release-activated calcium modulator 1
MGI:1925542

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Human Phenotypes	Decreased circulating IgA level	Decreased circulating IgG level	Decreased circulating total IgM	Lymphopenia	Abnormal natural killer cell count
Disease(s) Associated with ORAI1
immunodeficiency 9

Mouse Phenotypes		abnormal thymocyte activation	decreased platelet calcium level	abnormal mast cell physiology	abnormal B cell physiology	abnormal B cell activation	abnormal T cell physiology	abnormal T cell activation	abnormal platelet activation
Availability	Mouse Genotype	abnormal thymocyte activation	decreased platelet calcium level	abnormal mast cell physiology	abnormal B cell physiology	abnormal B cell activation	abnormal T cell physiology	abnormal T cell activation	abnormal platelet activation
	Orai1^Gt(XL922)Byg/Orai1^Gt(XL922)Byg
	Orai1^tm1Fesk/Orai1^tm1Fesk
	Orai1^tm1Rao/Orai1^tm1Rao
	Orai1^Gt(XL922)Byg/Orai1⁺
	Orai1^tm1Rao/Orai1⁺
	Orai1^tm1.1Hjm/Orai1^tm1.1Hjm Tg(Cd4-cre)1Cwi/0 (conditional)
	Cd79a^tm1(cre)Reth/Cd79a⁺ Orai1^tm1Smua/Orai1^tm1Smua (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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