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Symbol
Name
ID
Rras2
related RAS viral (r-ras) oncogene 2
MGI:1914172
Phenotype annotations related to hematopoietic system
Darker colors indicate more annotations
Human Phenotypes
Lymphopenia
Thrombocytopenia
Disease(s) Associated with RRAS2
Noonan syndrome 12

Mouse Phenotypes
decreased B cell proliferation
abnormal thymus morphology
enlarged thymus
decreased follicular B cell number
decreased marginal zone B cell number
decreased B cell number
increased NK cell number
decreased memory T cell number
decreased T cell number
decreased spleen weight
spleen hypoplasia
decreased spleen B cell follicle size
abnormal B cell physiology
abnormal B cell activation
abnormal CD4-positive, alpha-beta T cell physiology
abnormal CD8-positive, alpha-beta T cell physiology
Availability Mouse Genotype
Rras2em1(IMPC)Ccpcz/Rras2em1(IMPC)Ccpcz
Rras2Gt(OST361011)Lex/Rras2Gt(OST361011)Lex
Rras2Gt(OST361011)Lex/Rras2+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory