Symbol
Name
ID

Tnfrsf13b
tumor necrosis factor receptor superfamily, member 13b
MGI:1889411

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Human Phenotypes	Decreased circulating IgA level	Decreased circulating IgG level	Decreased circulating total IgM	Partial absence of specific antibody response to unconjugated pneumococcus vaccine	Impaired T cell function	Abnormal T cell count	Lymphoma	Splenomegaly
Disease(s) Associated with TNFRSF13B
common variable immunodeficiency 2

Mouse Phenotypes

increased B cell proliferation

enlarged spleen

increased spleen weight

abnormal class switch recombination

increased transitional stage B cell number

increased mature B cell number

increased follicular B cell number

increased marginal zone B cell number

increased B cell number

abnormal spleen morphology

abnormal spleen primary B follicle morphology

increased spleen germinal center size

abnormal spleen periarteriolar lymphoid sheath morphology

increased spleen white pulp amount

abnormal B cell activation

abnormal immunoglobulin level

decreased IgA level

decreased IgE level

decreased IgG1 level

increased IgG1 level

decreased IgM level

Availability

Mouse Genotype

Tnfrsf13b^tm1Cmac/Tnfrsf13b^tm1Cmac

Tnfrsf13b^tm1Rjb/Tnfrsf13b^tm1Rjb

Tnfrsf13b^tm1Vmd/Tnfrsf13b^tm1Vmd

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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