Symbol Name ID |
Aicda
activation-induced cytidine deaminase MGI:1342279 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Decreased circulating IgA level |
Decreased circulating IgG level |
Increased circulating IgM level |
Complete or near-complete absence of specific antibody response to tetanus vaccine |
Impaired Ig class switch recombination |
Disease(s) Associated with AICDA | |||||
immunodeficiency with hyper-IgM type 2 |
Mouse Phenotypes | hematopoietic system phenotype |
abnormal class switch recombination |
abnormal somatic hypermutation frequency |
increased mean corpuscular hemoglobin |
increased mean corpuscular hemoglobin concentration |
increased early germinal center B cell number |
decreased late germinal center B cell number |
increased germinal center B cell number |
decreased follicular B cell number |
increased leukocyte cell number |
abnormal splenic cell ratio |
decreased IgA level |
decreased IgE level |
decreased IgG1 level |
decreased IgG2a level |
decreased IgG2b level |
decreased IgG3 level |
decreased IgG level |
increased IgM level |
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Availability | Mouse Genotype | |||||||||||||||||||
Aicdaem1Jaych/Aicdaem1Jaych | * | |||||||||||||||||||
Aicdam1Btlr/Aicdam1Btlr | ||||||||||||||||||||
Aicdam2Btlr/Aicdam2Btlr | ||||||||||||||||||||
Aicdatm1.1Fwa/Aicdatm1.1Fwa | ||||||||||||||||||||
Aicdatm1b(EUCOMM)Hmgu/Aicdatm1b(EUCOMM)Hmgu | ||||||||||||||||||||
Aicdatm1Hon/Aicdatm1Hon | ||||||||||||||||||||
Aicdatm2.1Hon/Aicdatm2.1Hon | ||||||||||||||||||||
Aicdatm3.1Mnz/Aicdatm3.1Mnz | ||||||||||||||||||||
Aicdatm4.1Mnz/Aicdatm4.1Mnz | ||||||||||||||||||||
Aicdatm1Hon/Aicda+ | ||||||||||||||||||||
Aicdatm1Hon/Aicdatm1.1Fwa | ||||||||||||||||||||
Aicdatm1Hon/Aicdatm3Mnz | ||||||||||||||||||||
Aicdatm1Hon/Aicdatm4Mnz | ||||||||||||||||||||
Aicdatm3Mnz/Aicda+ | ||||||||||||||||||||
Aicdatm4Mnz/Aicda+ |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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