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Symbol
Name
ID
Slc40a1
solute carrier family 40 (iron-regulated transporter), member 1
MGI:1315204
Phenotype annotations related to hematopoietic system
*Aspects of the system are reported to show a normal phenotype.
!Indicates phenotype varies with strain background.
Darker colors indicate more annotations
Human Phenotypes
Anemia
Disease(s) Associated with SLC40A1
hemochromatosis type 4

Mouse Phenotypes
hematopoietic system phenotype
increased splenocyte apoptosis
anemia
hypochromic microcytic anemia
abnormal erythrocyte morphology
increased erythrocyte cell number
polycythemia
decreased hematocrit
increased hematocrit
decreased hemoglobin content
increased hemoglobin content
decreased mean corpuscular hemoglobin
decreased mean corpuscular volume
increased mean corpuscular volume
anisocytosis
leptocytosis
poikilocytosis
reticulocytosis
abnormal spleen development
decreased spleen iron level
increased spleen iron level
small spleen
abnormal macrophage physiology
Availability Mouse Genotype
Slc40a1ffe/Slc40a1ffe
Slc40a1Pcm/Slc40a1Pcm
Slc40a1tm1.1Mmfe/Slc40a1tm1.1Mmfe
Slc40a1ffe/Slc40a1+
Slc40a1Pcm/Slc40a1+ !
Slc40a1tm1.1Mmfe/Slc40a1+
Slc40a1tm1Nca/Slc40a1+ *
Meox2tm1(cre)Sor/Meox2+
Slc40a1tm2Nca/Slc40a1tm2Nca  (conditional)
Slc40a1tm2Nca/Slc40a1tm2Nca
Tg(Vil1-cre/ERT2)23Syr/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory