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Symbol
Name
ID
Elavl1
ELAV like RNA binding protein 1
MGI:1100851
Phenotype annotations related to hematopoietic system
Darker colors indicate more annotations

Mouse Phenotypes
decreased B cell apoptosis
increased T cell apoptosis
abnormal macrophage chemotaxis
decreased T cell proliferation
thymus hypoplasia
abnormal thymocyte activation
abnormal definitive hematopoiesis
decreased common myeloid progenitor cell number
abnormal positive T cell selection
increased double-negative T cell number
decreased double-positive T cell number
increased double-positive T cell number
decreased bone marrow cell number
decreased erythroid progenitor cell number
decreased mean corpuscular hemoglobin
decreased granulocyte number
increased granulocyte number
decreased T-helper 17 cell number
decreased CD4-positive, alpha-beta T cell number
decreased CD8-positive, alpha-beta T cell number
increased single-positive T cell number
increased macrophage cell number
increased monocyte cell number
decreased leukocyte cell number
abnormal myeloid leukocyte morphology
abnormal spleen development
spleen hypoplasia
absent spleen
abnormal B cell physiology
abnormal T cell physiology
Availability Mouse Genotype
Elavl1tm1.1Thla/Elavl1+
Elavl1tm1b(EUCOMM)Hmgu/Elavl1+
Elavl1tm1.1Atas/Elavl1tm1.1Atas
Tnfrsf4tm2(cre)Nik/Tnfrsf4+  (conditional)
Elavl1tm1.1Dkon/Elavl1tm1.1Dkon
Lyz2tm1(cre)Ifo/Lyz2+  (conditional)
Elavl1tm1Dkon/Elavl1tm1Dkon
Edil3Tg(Sox2-cre)1Amc/Edil3+  (conditional)
Elavl1tm1Dkon/Elavl1tm1Dkon
Tg(Lck-cre)I57Jxm/0  (conditional)
Elavl1tm1Thla/Elavl1tm1Thla
Gt(ROSA)26Sortm1(cre/ERT2)Alj/Gt(ROSA)26Sor+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory