|
Symbol Name ID |
Stim1
stromal interaction molecule 1 MGI:107476 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Decreased circulating IgA level |
Increased circulating IgA level |
Decreased circulating IgG level |
Increased circulating IgG3 level |
Decreased circulating total IgM |
Abnormal bleeding |
Epistaxis |
Subarachnoid hemorrhage |
Bruising susceptibility |
Purpura |
Anemia |
Autoimmune hemolytic anemia |
Howell-Jolly bodies |
Abnormal lymphocyte count |
Abnormality of coagulation |
Abnormality of thrombocytes |
Thrombocytopenia |
Autoimmune thrombocytopenia |
Asplenia |
Hypoplastic spleen |
Splenomegaly |
| Disease(s) Associated with STIM1 | |||||||||||||||||||||
| immunodeficiency 10 | |||||||||||||||||||||
| Stormorken syndrome |
| Mouse Phenotypes | hematopoietic system phenotype |
decreased B cell proliferation |
decreased mast cell degranulation |
enlarged spleen |
increased spleen weight |
abnormal thrombopoiesis |
abnormal megakaryocyte morphology |
increased megakaryocyte cell number |
increased neutrophil cell number |
thrombocytopenia |
increased mean platelet volume |
decreased NK cell number |
decreased NK T cell number |
decreased regulatory T cell number |
decreased lymphocyte cell number |
increased lymphocyte cell number |
increased Ly6C high monocyte number |
decreased Ly6C low monocyte number |
increased monocyte cell number |
increased leukocyte cell number |
abnormal spleen morphology |
increased spleen red pulp amount |
abnormal B cell physiology |
abnormal CD4-positive, alpha-beta T cell physiology |
abnormal platelet activation |
decreased platelet aggregation |
|
| Availability | Mouse Genotype | ||||||||||||||||||||||||||
| Stim1Gt(RRS558)Byg/Stim1Gt(RRS558)Byg | * | ||||||||||||||||||||||||||
| Stim1tm1.1Kuro/Stim1tm1.1Kuro | |||||||||||||||||||||||||||
| Stim1em1(IMPC)Mbp/Stim1+ | |||||||||||||||||||||||||||
| Stim1Sax/Stim1+ | |||||||||||||||||||||||||||
| Stim1tm1.1Pg/Stim1+ | |||||||||||||||||||||||||||
| Stim1tm3Ics/Stim1+ | |||||||||||||||||||||||||||
| Stim1tm1Kuro/Stim1tm1Kuro Cd79atm1(cre)Reth/Cd79a+ (conditional) |
|||||||||||||||||||||||||||
| Stim1tm1Rao/Stim1tm1Rao Tg(Cd4-cre)1Cwi/0 (conditional) |
|||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 05/14/2024 MGI 6.23 |
|
|
|
||
Analysis Tools