Symbol
Name
ID

Ppp3cb
protein phosphatase 3, catalytic subunit, beta isoform
MGI:107163

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Mouse Phenotypes

increased CD8-positive, alpha-beta memory T cell proliferation

decreased T cell proliferation

decreased thymus weight

thymus hypoplasia

abnormal T cell differentiation

increased central memory CD4-positive, alpha-beta T cell number

decreased CD4-positive, alpha-beta T cell number

increased central memory CD8 positive, alpha-beta T cell number

increased effector memory CD8-positive, alpha-beta T cell number

decreased CD8-positive, alpha-beta memory T cell number

decreased CD8-positive, naive alpha-beta T cell number

decreased CD8-positive, alpha-beta T cell number

decreased memory-marker CD4-positive NK T cell number

decreased CD4-positive NK T cell number

decreased NK T cell number

decreased alpha-beta T cell number

increased effector memory T-helper cell number

decreased T-helper cell number

decreased T cell number

decreased single-positive T cell number

abnormal lymphocyte morphology

abnormal T cell morphology

abnormal NK cell physiology

abnormal CD4-positive, alpha-beta T cell physiology

abnormal CD8-positive, alpha-beta T cell physiology

Availability

Mouse Genotype

Ppp3cb^{em1(IMPC)Ccpcz}/Ppp3cb^{em1(IMPC)Ccpcz}

Ppp3cb^M1Btlr/Ppp3cb^M1Btlr

Ppp3cb^m2Btlr/Ppp3cb^m2Btlr

Ppp3cb^M3Btlr/Ppp3cb^M3Btlr

Ppp3cb^M4Btlr/Ppp3cb^M4Btlr

Ppp3cb^m5Btlr/Ppp3cb^m5Btlr

Ppp3cb^M6Btlr/Ppp3cb^M6Btlr

Ppp3cb^tm1Jmk/Ppp3cb^tm1Jmk

Ppp3cb^M1Btlr/Ppp3cb⁺

Ppp3cb^m2Btlr/Ppp3cb⁺

Ppp3cb^M3Btlr/Ppp3cb⁺

Ppp3cb^M4Btlr/Ppp3cb⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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