Symbol
Name
ID

Tle4
transducin-like enhancer of split 4
MGI:104633

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Mouse Phenotypes

increased thymocyte apoptosis

abnormal thymus morphology

thymus atrophy

thymus hypoplasia

decreased DN2 thymocyte number

enlarged spleen

decreased common myeloid progenitor cell number

abnormal lymphopoiesis

decreased pre-pro B cell number

decreased double-positive T cell number

decreased bone marrow cell number

decreased follicular B cell number

decreased B cell number

increased NK T cell number

decreased lymphocyte cell number

decreased leukocyte cell number

decreased hematopoietic stem cell number

abnormal spleen morphology

spleen hypoplasia

decreased spleen B cell follicle number

abnormal hematopoietic stem cell physiology

Availability

Mouse Genotype

Tle4^em1(IMPC)Mbp/Tle4^em1(IMPC)Mbp

Tle4^tm1.2Dasw/Tle4^tm1.2Dasw

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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