Symbol
Name
ID

Tpp2
tripeptidyl peptidase II
MGI:102724

Phenotype annotations related to hematopoietic system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Mouse Phenotypes

hematopoietic system phenotype

increased T cell apoptosis

thymus atrophy

enlarged spleen

abnormal CD4-positive T cell differentiation

abnormal CD8-positive, alpha-beta T cell differentiation

increased double-negative T cell number

decreased double-positive T cell number

extramedullary hematopoiesis

increased B cell number

decreased CD8-positive, alpha-beta T cell number

increased memory T cell number

decreased T cell number

increased T cell number

increased single-positive T cell number

decreased leukocyte cell number

abnormal spleen morphology

increased spleen red pulp amount

abnormal splenic cell ratio

abnormal lymphocyte physiology

abnormal cytotoxic T cell physiology

Availability

Mouse Genotype

Tpp2^{Gt(OST432061)Lex}/Tpp2^{Gt(OST432061)Lex}

Tpp2^tm1.1Gnie/Tpp2^tm1.1Gnie

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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