|
Symbol Name ID |
Naglu
alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB) MGI:1351641 |
| Darker colors indicate more annotations |
| Human Phenotypes | Abnormality of the middle ear ossicles |
Otitis media |
Chronic otitis media |
Conductive hearing impairment |
Mixed hearing impairment |
Thickened helices |
Sensorineural hearing impairment |
Hearing impairment |
| Disease(s) Associated with NAGLU | ||||||||
| mucopolysaccharidosis III | ||||||||
| mucopolysaccharidosis type IIIB |
| Mouse Phenotypes | abnormal middle ear ossicle morphology |
abnormal stapes morphology |
abnormal inner ear morphology |
abnormal cochlea morphology |
abnormal Reissner membrane morphology |
decreased cochlear hair cell number |
abnormal organ of Corti morphology |
organ of Corti degeneration |
abnormal spiral ligament morphology |
abnormal spiral limbus morphology |
abnormal crista ampullaris morphology |
abnormal inner ear vestibule morphology |
abnormal middle ear morphology |
increased or absent threshold for auditory brainstem response |
conductive hearing loss |
increased susceptibility to otitis media |
|
| Availability | Mouse Genotype | ||||||||||||||||
| Naglutm1Efn/Naglutm1Efn | |||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 05/28/2024 MGI 6.13 |
|
|
|
||
Analysis Tools