Symbol Name ID |
Polg
polymerase (DNA directed), gamma MGI:1196389 |
Darker colors indicate more annotations |
Human Phenotypes | Abnormal vestibular function |
Sensorineural hearing impairment |
Bilateral sensorineural hearing impairment |
Hearing impairment |
Disease(s) Associated with POLG | ||||
autosomal dominant progressive external ophthalmoplegia 1 | ||||
autosomal recessive progressive external ophthalmoplegia 1 | ||||
mitochondrial DNA depletion syndrome 4b | ||||
sensory ataxic neuropathy, dysarthria, and ophthalmoparesis |
Mouse Phenotypes | cochlear outer hair cell degeneration |
cochlear hair cell degeneration |
stria vascularis degeneration |
increased or absent threshold for auditory brainstem response |
increased susceptibility to age-related hearing loss |
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Availability | Mouse Genotype | |||||
Polgtm1Prol/Polgtm1Prol |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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