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Symbol
Name
ID
Lipa
lysosomal acid lipase A
MGI:96789
Phenotype annotations related to growth/size/body
Darker colors indicate more annotations
Human Phenotypes
Splenomegaly
Hepatosplenomegaly
Ascites
Hepatomegaly
Abdominal distention
Protuberant abdomen
Failure to thrive
Cachexia
Growth delay
Disease(s) Associated with LIPA
cholesterol ester storage disease
Wolman disease

Mouse Phenotypes
decreased body weight
decreased susceptibility to diet-induced obesity
enlarged liver
hepatosplenomegaly
increased liver weight
enlarged spleen
increased spleen weight
Availability Mouse Genotype
Lipatm1Ggb/Lipatm1Ggb
Lipatm1c(EUCOMM)Hmgu/Lipatm1c(EUCOMM)Hmgu
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1Tg(Alb-cre)21Mgn  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory