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Symbol
Name
ID

Tshr
thyroid stimulating hormone receptor
MGI:98849

Phenotype annotations related to endocrine/exocrine glands

Darker colors indicate more annotations

Human Phenotypes	Increased circulating free T3	Increased circulating free T4 concentration	Increased circulating T4 concentration	Decreased thyroid-stimulating hormone level	Goiter	Thyroid hyperplasia	Hyperthyroidism	Thyrotoxicosis with diffuse goiter	Graves disease	Activating thyroid-stimulating hormone receptor defect
Disease(s) Associated with TSHR	Increased circulating free T3	Increased circulating free T4 concentration	Increased circulating T4 concentration	Decreased thyroid-stimulating hormone level	Goiter	Thyroid hyperplasia	Hyperthyroidism	Thyrotoxicosis with diffuse goiter	Graves disease	Activating thyroid-stimulating hormone receptor defect
Graves' disease
nonautoimmune hyperthyroidism

Mouse Phenotypes		increased thyrotroph cell number	abnormal thyroid follicle morphology	small thyroid gland	abnormal thyroid gland physiology	decreased activity of thyroid gland	iodide oxidation defect
Availability	Mouse Genotype	increased thyrotroph cell number	abnormal thyroid follicle morphology	small thyroid gland	abnormal thyroid gland physiology	decreased activity of thyroid gland	iodide oxidation defect
	Tshr^hyt-2J/Tshr^hyt-2J
	Tshr^hyt-3J/Tshr^hyt-3J
	Tshr^hyt/Tshr^hyt
	Tshr^tm1Rmar/Tshr^tm1Rmar

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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