About   Help   FAQ
Symbol
Name
ID
Tgfbr2
transforming growth factor, beta receptor II
MGI:98729
Phenotype annotations related to endocrine/exocrine glands
Darker colors indicate more annotations
Human Phenotypes
Diabetes mellitus
Exocrine pancreatic insufficiency
Neoplasm of the pancreas
Pancreatic adenocarcinoma
Pituitary adenoma
Neoplasm of the thyroid gland
Disease(s) Associated with TGFBR2
Lynch syndrome
pancreatic cancer

Mouse Phenotypes
abnormal parathyroid gland morphology
absent parathyroid glands
parathyroid hypoplasia
small thymus
abnormal pancreas development
increased prostate gland adenocarcinoma incidence
increased prostate intraepithelial neoplasia incidence
increased T cell derived lymphoma incidence
pancreas inflammation
Availability Mouse Genotype
Tg(CD2-Tgfbr2)1Grs/?
Ptf1atm1.1(cre)Cvw/Ptf1a+
Tgfbr2tm1.2Hlm/Tgfbr2tm1.2Hlm  (conditional)
Tgfbr2tm1.2Hlm/Tgfbr2tm1.2Hlm
Tg(Col1a2-cre/ERT,-ALPP)7Cpd/0  (conditional)
Tgfbr2tm1Karl/Tgfbr2tm1Karl
Tg(Mx1-cre)1Cgn/0  (conditional)
Tgfbr2tm1Karl/Tgfbr2tm1Karl
H2az2Tg(Wnt1-cre)11Rth/H2az2+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/14/2024
MGI 6.23
The Jackson Laboratory