Symbol
Name
ID

Shh
sonic hedgehog
MGI:98297

Phenotype annotations related to endocrine/exocrine glands

Darker colors indicate more annotations

Human Phenotypes	Diabetes mellitus	Decreased response to growth hormone stimulation test	Anterior hypopituitarism	Panhypopituitarism	Neoplasm of the thyroid gland	Diabetes insipidus	Central diabetes insipidus
Disease(s) Associated with SHH	Diabetes mellitus	Decreased response to growth hormone stimulation test	Anterior hypopituitarism	Panhypopituitarism	Neoplasm of the thyroid gland	Diabetes insipidus	Central diabetes insipidus
Hirschsprung's disease
holoprosencephaly
holoprosencephaly 3
solitary median maxillary central incisor

Mouse Phenotypes

abnormal submandibular gland morphology

abnormal cystic duct morphology

abnormal adrenal gland morphology

abnormal adrenocortical cell morphology

enlarged adrenocortical cells

thin adrenal cortex

small adrenal glands

small gallbladder

abnormal gallbladder smooth muscle morphology

annular pancreas

abnormal adrenal gland physiology

Availability

Mouse Genotype

Shh^{tm1(EGFP/cre)Cjt}/Shh^{tm1(EGFP/cre)Cjt}

Shh^tm1Amc/Shh^tm1Amc

Shh^tm2Amc/Shh^tm2.1Amc
Tg(Nr5a1-cre)2Klp/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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