About Help FAQ

Symbol
Name
ID

Pcsk1
proprotein convertase subtilisin/kexin type 1
MGI:97511

Phenotype annotations related to endocrine/exocrine glands

Darker colors indicate more annotations

Human Phenotypes	Hyperinsulinemia	Hypoinsulinemia	Decreased circulating cortisol level	Elevated circulating proinsulin concentration	Decreased response to growth hormone stimulation test	Central adrenal insufficiency	Gonadotropin deficiency	Pituitary hypothyroidism	Delayed puberty	Hypogonadotropic hypogonadism
Disease(s) Associated with PCSK1
proprotein convertase 1/3 deficiency

Mouse Phenotypes		abnormal pancreatic islet morphology	decreased testis weight	abnormal pituitary gland physiology	abnormal pancreas physiology
Availability	Mouse Genotype	abnormal pancreatic islet morphology	decreased testis weight	abnormal pituitary gland physiology	abnormal pancreas physiology
	Pcsk1^em2Irli/Pcsk1^em2Irli
	Pcsk1^N222D/Pcsk1^N222D

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/14/2024 MGI 6.23