Symbol
Name
ID

Drd2
dopamine receptor D2
MGI:94924

Phenotype annotations related to endocrine/exocrine glands

Darker colors indicate more annotations

Human Phenotypes	Type II diabetes mellitus
Disease(s) Associated with DRD2	Type II diabetes mellitus
type 2 diabetes mellitus

Mouse Phenotypes

adenohypophysis peliosis

abnormal adrenal gland zona fasciculata morphology

abnormal adrenal gland zona reticularis morphology

enlarged adrenocortical cells

adrenal cortical hyperplasia

abnormal pituitary gland morphology

abnormal adenohypophysis morphology

decreased gonadotroph cell number

decreased lactotroph cell size

increased lactotroph cell number

decreased somatotroph cell number

increased thyrotroph cell number

adenohypophysis hyperplasia

adenohypophysis hypertrophy

increased pituitary gland weight

enlarged pituitary gland

pituitary gland hyperplasia

abnormal melanotroph morphology

enlarged pituitary intermediate lobe

pituitary intermediate lobe hyperplasia

small ovary

small testis

increased pituitary adenoma incidence

hypersecretion of corticosterone

abnormal pituitary gland physiology

Availability

Mouse Genotype

Drd2^tm1Ebo/Drd2^tm1Ebo

Drd2^tm1Low/Drd2^tm1Low

Drd2^tm1Mok/Drd2^tm1Mok

Drd2^tm1.1Mrub/Drd2^tm1.1Mrub
Tg(Nes-cre)1Kln/? (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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