Symbol Name ID |
Apc
APC, WNT signaling pathway regulator MGI:88039 |
Darker colors indicate more annotations |
Human Phenotypes | Diabetes mellitus |
Exocrine pancreatic insufficiency |
Pancreatic adenocarcinoma |
Small intestine carcinoid |
Adrenocortical adenoma |
Adrenocortical carcinoma |
Papillary thyroid carcinoma |
Disease(s) Associated with APC | |||||||
familial adenomatous polyposis 1 | |||||||
pancreatic cancer |
Mouse Phenotypes | abnormal large intestine crypts of Lieberkuhn morphology |
abnormal small intestine crypts of Lieberkuhn morphology |
salivary gland epithelial hyperplasia |
adrenal gland hyperplasia |
decreased pancreatic beta cell mass |
decreased pancreatic islet number |
abnormal thymus morphology |
abnormal Hassall's corpuscle morphology |
small thymus |
thymus hypoplasia |
decreased thymocyte number |
abnormal mammary gland development |
absent nipple |
increased mammary gland tumor incidence |
increased mammary adenocarcinoma incidence |
mammary gland hyperplasia |
absent male preputial gland |
prostate gland epithelial hyperplasia |
Harderian gland hyperplasia |
abnormal pancreas development |
absent corpus luteum |
abnormal ovarian follicle morphology |
absent mature ovarian follicles |
abnormal ovarian folliculogenesis |
ovary atrophy |
ovary cyst |
increased ovary tumor incidence |
increased granulosa cell tumor incidence |
increased prostate gland adenocarcinoma incidence |
increased prostate intraepithelial neoplasia incidence |
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Availability | Mouse Genotype | ||||||||||||||||||||||||||||||
Apctm1Rfo/Apctm1Rfo | |||||||||||||||||||||||||||||||
ApcM1Tno/Apc+ | |||||||||||||||||||||||||||||||
ApcMin/Apc+ | |||||||||||||||||||||||||||||||
Apctm1Cip/Apc+ | |||||||||||||||||||||||||||||||
Apctm2Rfo/Apc+ | |||||||||||||||||||||||||||||||
Apctm1Kk/Apctm1Kk Tg(Lck-cre)1Cwi/? (conditional) |
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Apctm1Rsmi/Apctm1Rsmi Pgrtm2(cre)Lyd/Pgr+ (conditional) |
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Apctm1Tno/Apctm1Tno Tg(Pbsn-cre)4Prb/0 (conditional) |
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Apctm2.1Cip/Apctm2.1Cip Tg(Vil1-cre/ERT2)23Syr/0 (conditional) |
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Apctm2Rak/Apctm2Rak Tg(KRT14-cre)8Brn/0 (conditional) |
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Apctm2Rak/Apctm2Rak Tg(Pdx1-cre)6Tuv/0 (conditional) |
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Apctm1Tno/Apc+ Tg(CDX2-cre)101Erf/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/28/2024 MGI 6.13 |
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