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Symbol
Name
ID
Fbxw7
F-box and WD-40 domain protein 7
MGI:1354695
Phenotype annotations related to endocrine/exocrine glands
Darker colors indicate more annotations

Mouse Phenotypes
bile duct hyperplasia
dilated bile duct
enlarged thymus
thymus hypoplasia
abnormal seminiferous tubule epithelium morphology
abnormal Sertoli cell barrier morphology
abnormal Sertoli cell morphology
decreased Sertoli cell number
ectopic Sertoli cells
seminiferous tubule degeneration
abnormal testis development
decreased testis weight
small testis
testicular atrophy
testis degeneration
increased T cell derived lymphoma incidence
Availability Mouse Genotype
Fbxw7tm1Iaai/Fbxw7tm1Iaai
Tg(Lck-cre)1Cwi/0  (conditional)
Fbxw7tm1Iaai/Fbxw7tm1Iaai
Tg(Mx1-cre)1Cgn/0  (conditional)
Fbxw7tm1Iaai/Fbxw7tm1Iaai
Tg(Amh-cre)8815Reb/0  (conditional)
Fbxw7tm1Iken/Fbxw7tm1Iken
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+  (conditional)
Fbxw7tm1Kei/Fbxw7tm1Kei
Tg(Lck-cre)1Cwi/?  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory