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Symbol Name ID |
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box MGI:1202879 |
| Darker colors indicate more annotations |
| Human Phenotypes | Diabetes mellitus |
Type II diabetes mellitus |
Exocrine pancreatic insufficiency |
Pancreatic adenocarcinoma |
| Disease(s) Associated with TCF7L2 | ||||
| pancreatic cancer | ||||
| type 2 diabetes mellitus |
| Mouse Phenotypes | abnormal colon goblet cell morphology |
abnormal crypts of Lieberkuhn morphology |
decreased Paneth cell number |
absent Paneth cells |
ectopic Paneth cells |
decreased pancreatic beta cell mass |
enlarged adenohypophysis |
abnormal neurohypophysis morphology |
enlarged pituitary gland |
abnormal pituitary intermediate lobe morphology |
decreased insulin secretion |
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| Availability | Mouse Genotype | |||||||||||
| Tcf7l2tm1.1(EGFP/cre)Mrc/Tcf7l2tm1.1(EGFP/cre)Mrc | ||||||||||||
| Tcf7l2tm1a(EUCOMM)Wtsi/Tcf7l2tm1a(EUCOMM)Wtsi | ||||||||||||
| Tcf7l2tm1Cle/Tcf7l2tm1Cle | ||||||||||||
| Tcf7l2tm2.2Mrc/Tcf7l2tm2.2Mrc | ||||||||||||
| Tcf7l2tm1Geno/Tcf7l2tm1Geno Tg(Pdx1-cre)89.1Dam/0 (conditional) |
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| Tcf7l2tm2.1Cle/Tcf7l2tm2.1Cle Tg(Vil1-cre/ERT2)23Syr/0 (conditional) |
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| Tcf7l2tm1(EGFP/cre)Mrc/Tcf7l2tm2.1Mrc (conditional) | ||||||||||||
| Tcf7l2tm1.1(EGFP/cre)Mrc/Tcf7l2tm2.1Mrc (conditional) | ||||||||||||
| Tcf7l2tm1.1(EGFP/cre)Mrc/Tcf7l2tm2.2Mrc (conditional) | ||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/21/2024 MGI 6.23 |
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