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Symbol
Name
ID
Esr2
estrogen receptor 2 (beta)
MGI:109392
Phenotype annotations related to endocrine/exocrine glands
Darker colors indicate more annotations
Human Phenotypes
Diabetes mellitus
Type I diabetes mellitus
Type II diabetes mellitus
Decreased cirrculating antimullerian hormone circulation
Elevated circulating follicle stimulating hormone level
Elevated circulating luteinizing hormone level
Decreased serum estradiol
Increased circulating free T3
Increased circulating free T4 concentration
Decreased thyroid-stimulating hormone level
Goiter
Graves disease
Disease(s) Associated with ESR2
coronary artery disease
Graves' disease
ovarian dysgenesis 8
pre-eclampsia

Mouse Phenotypes
abnormal large intestine crypts of Lieberkuhn morphology
enlarged pancreatic islets
abnormal mammary gland growth during lactation
abnormal mammary gland growth during pregnancy
abnormal mammary gland epithelium morphology
mammary gland alveolar hyperplasia
prostate gland epithelial hyperplasia
absent corpus luteum
decreased corpora lutea number
abnormal cumulus oophorus morphology
absent mature ovarian follicles
increased secondary ovarian follicle number
increased atretic ovarian follicle number
impaired ovarian folliculogenesis
abnormal tertiary ovarian follicle morphology
decreased insulin secretion
Availability Mouse Genotype
Esr2tm1.1Gust/Esr2tm1.1Gust
Esr2tm1.2Pcn/Esr2tm1.2Pcn
Esr2tm1Mma/Esr2tm1Mma
Esr2tm1Unc/Esr2tm1Unc

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory