Symbol
Name
ID

Sox17
SRY (sex determining region Y)-box 17
MGI:107543

Phenotype annotations related to endocrine/exocrine glands

!	Indicates phenotype varies with strain background.
	Darker colors indicate more annotations

Human Phenotypes	Increased circulating cortisol level
Disease(s) Associated with SOX17	Increased circulating cortisol level
vesicoureteral reflux

Mouse Phenotypes

abnormal bile duct development

abnormal extrahepatic bile duct morphology

abnormal common bile duct morphology

abnormal cystic duct morphology

biliary atresia

thymus hypoplasia

abnormal gallbladder morphology

abnormal gallbladder epithelium morphology

abnormal gallbladder size

small gallbladder

abnormal gallbladder smooth muscle morphology

absent gallbladder

absent pancreas

ovary atrophy

Availability

Mouse Genotype

Sox17^tm1Sjm/Sox17^tm1Sjm

Sox17^SHIVA/Sox17⁺

Sox17^tm1Ysk/Sox17⁺

Sox17^tm1Jaw/Sox17^tm1Jaw
Tg(Foxa3-cre)1Khk/0 (conditional)

Sox17^tm1Jaw/Sox17^tm1Jaw
Tg(Pdx1-cre)6Tuv/0 (conditional)

Sox17^tm1Jaw/Sox17^tm1Sjm
Tg(Foxa3-cre)1Khk/0 (conditional)

Sox17^tm1Jaw/Sox17^tm1Sjm
Tg(Pdx1-cre)6Tuv/0 (conditional)

Sox17^tm1Sjm/Sox17^tm2Sjm
Tg(Mx1-cre)1Cgn/0 (conditional)

Sox17^tm2Sjm/Sox17⁺
Tg(Pdx1-cre)6Tuv/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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