Symbol
Name
ID

Ptpn22
protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
MGI:107170

Phenotype annotations related to endocrine/exocrine glands

Darker colors indicate more annotations

Human Phenotypes

Diabetes mellitus

Type II diabetes mellitus

Thymoma

Abnormality of the endocrine system

Increased circulating free T3

Increased circulating free T4 concentration

Decreased thyroid-stimulating hormone level

Adrenal hypoplasia

Adrenal insufficiency

Goiter

Graves disease

Diabetes insipidus

Disease(s) Associated with PTPN22

Addison's disease

coronary artery disease

Graves' disease

myasthenia gravis

temporal arteritis

type 1 diabetes mellitus

Mouse Phenotypes		abnormal salivary gland morphology	abnormal thymus morphology	enlarged thymus	thymus hyperplasia	abnormal thymocyte activation
Availability	Mouse Genotype	abnormal salivary gland morphology	abnormal thymus morphology	enlarged thymus	thymus hyperplasia	abnormal thymocyte activation
	Ptpn22^tm1.1Draw/Ptpn22^tm1.1Draw
	Ptpn22^tm1.1Kas/Ptpn22^tm1.1Kas
	Ptpn22^tm2Achn/Ptpn22^tm2Achn
	Ptpn22^tm1.1Draw/Ptpn22⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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