Symbol
Name
ID

Hes1
hes family bHLH transcription factor 1
MGI:104853

Phenotype annotations related to endocrine/exocrine glands

Darker colors indicate more annotations

Mouse Phenotypes

abnormal pancreatic beta cell differentiation

abnormal exocrine pancreas morphology

abnormal bile duct morphology

abnormal bile duct development

abnormal extrahepatic bile duct morphology

abnormal common bile duct morphology

abnormal cystic duct morphology

increased solitary pulmonary neuroendocrine cell number

abnormal pituitary gland development

pituitary gland hypoplasia

thymus hypoplasia

decreased DN1 thymic pro-T cell number

decreased DN2 thymocyte number

decreased DN3 thymocyte number

decreased DN4 thymocyte number

increased DN1 thymic pro-T cell number

absent gallbladder

abnormal pancreas development

abnormal pancreas morphology

Availability

Mouse Genotype

Hes1^tm1Fgu/Hes1^tm1Fgu

Hes1^tm1Fgu/Hes1⁺

Hes1^tm1.1Frad/Hes1^tm1.1Frad
Tg(Mx1-cre)1Cgn/0 (conditional)

Hes1^tm1Kag/Hes1^tm1Kag
Foxa2^{tm3.1(icre)Heli}/Foxa2⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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