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Symbol
Name
ID

Hsd11b1
hydroxysteroid 11-beta dehydrogenase 1
MGI:103562

Phenotype annotations related to endocrine/exocrine glands

Darker colors indicate more annotations

Human Phenotypes	Type I diabetes mellitus	Type II diabetes mellitus	Low tetrahydrocortisol (THF) plus 5-alpha-THF/tetrahydrocortisone (THE) ratio	Premature pubarche
Disease(s) Associated with HSD11B1	Type I diabetes mellitus	Type II diabetes mellitus		Premature pubarche
cortisone reductase deficiency 2
pre-eclampsia
type 2 diabetes mellitus

Mouse Phenotypes		enlarged adrenal glands
Availability	Mouse Genotype	enlarged adrenal glands
	Hsd11b1^tm1.1Ggla/Hsd11b1^tm1.1Ggla
	Hsd11b1^tm1Yko/Hsd11b1^tm1Yko
	Hsd11b1^tm1Ggla/Hsd11b1^tm1Ggla Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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