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Symbol
Name
ID
Dll4
delta like canonical Notch ligand 4
MGI:1859388
Phenotype annotations related to embryo
Darker colors indicate more annotations
Human Phenotypes
Oligohydramnios
Decreased fetal movement
Disease(s) Associated with DLL4
Adams-Oliver syndrome

Mouse Phenotypes
abnormal umbilical artery morphology
abnormal placenta vasculature
abnormal vitelline vasculature morphology
absent vitelline blood vessels
embryo tissue necrosis
abnormal embryo development
embryonic growth retardation
abnormal visceral yolk sac morphology
abnormal vitelline vascular remodeling
Availability Mouse Genotype
Dll4tm1Jrt/Dll4tm1Jrt
Dll4tm1Grid/Dll4+
Dll4tm1Jrt/Dll4+
Dll4tm1Nwg/Dll4+
Dll4tm2.1Vlcg/Dll4+
Tg(Nanog-cre)#Vlcg/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory