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Symbol
Name
ID

Pten
phosphatase and tensin homolog
MGI:109583

Phenotype annotations related to embryo

Darker colors indicate more annotations

Mouse Phenotypes

abnormal placenta vasculature

abnormal embryo development

abnormal developmental patterning

abnormal gastrulation

failure of initiation of embryo turning

incomplete embryo turning

abnormal rostral-caudal axis patterning

embryonic growth arrest

embryonic growth retardation

decreased embryo size

abnormal embryonic tissue morphology

open neural tube

kinked neural tube

wavy neural tube

abnormal somite development

disorganized embryonic tissue

abnormal allantois morphology

enlarged allantois

abnormal placenta morphology

abnormal maternal decidual layer morphology

decreased uterine NK cell number

abnormal placenta labyrinth morphology

abnormal trophoblast layer morphology

failure of chorioallantoic fusion

Availability

Mouse Genotype

Pten^m1un/Pten^m1un

Pten^tm1.1Gle/Pten^tm1.1Gle

Pten^tm1.1Hwu/Pten^tm1.1Hwu

Pten^tm1.1Mro/Pten^tm1.1Mro

Pten^tm1.2Mwst/Pten^tm1.2Mwst

Pten^tm1Mak/Pten^tm1Mak

Pten^tm1Rps/Pten^tm1Rps

Pten^tm2.1Gle/Pten^tm2.1Gle

Pten^tm1Mak/Pten⁺

Tg(Pten)1Srn/0

Amhr2^tm3(cre)Bhr/Amhr2⁺
Pten^tm1Hwu/Pten^tm1Hwu (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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