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Symbol Name ID |
Sox11
SRY (sex determining region Y)-box 11 MGI:98359 |
| Darker colors indicate more annotations |
| Human Phenotypes | Sparse scalp hair |
Microcephaly |
Full cheeks |
Midface retrusion |
Short chin |
Everted lower lip vermilion |
Short philtrum |
Thick vermilion border |
High palate |
Open mouth |
Delayed eruption of teeth |
Low hanging columella |
Anteverted nares |
Underdeveloped nasal alae |
Depressed nasal bridge |
Long nose |
Short nose |
Highly arched eyebrow |
Long eyelashes |
Short palpebral fissure |
Underdeveloped supraorbital ridges |
| Disease(s) Associated with SOX11 | |||||||||||||||||||||
| Coffin-Siris syndrome 9 |
| Mouse Phenotypes | abnormal craniofacial morphology |
wide cranial sutures |
abnormal cranium morphology |
small Meckel's cartilage |
abnormal pterygoid process morphology |
abnormal mandible morphology |
mandible hypoplasia |
short mandible |
maxilla hypoplasia |
abnormal palatal mesenchymal cell proliferation |
abnormal secondary palate development |
delayed palatal shelf elevation |
palatal shelves fail to meet at midline |
decreased palatal shelf size |
cleft upper lip |
cleft secondary palate |
cleft palate |
median cleft palate |
abnormal tongue position |
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| Availability | Mouse Genotype | |||||||||||||||||||
| Sox11tm1Weg/Sox11tm1Weg | ||||||||||||||||||||
| Sox11tm2.2Weg/Sox11tm2.2Weg | ||||||||||||||||||||
| Sox11tm1.1Gan/Sox11tm1.1Gan Tg(EIIa-cre)C5379Lmgd/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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