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Symbol
Name
ID

Gsk3b
glycogen synthase kinase 3 beta
MGI:1861437

Phenotype annotations related to craniofacial

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Tongue atrophy	Xerostomia
Disease(s) Associated with GSK3B	Tongue atrophy	Xerostomia
amyotrophic lateral sclerosis

Mouse Phenotypes		craniofacial phenotype	abnormal palate development	failure of palatal shelf elevation	palatal shelves fail to meet at midline	cleft secondary palate	complete cleft palate
Availability	Mouse Genotype	craniofacial phenotype	abnormal palate development	failure of palatal shelf elevation	palatal shelves fail to meet at midline	cleft secondary palate	complete cleft palate
	Gsk3b^tm1.2Ypc/Gsk3b^tm1.2Ypc
	Gsk3b^tm1Grc/Gsk3b^tm1Grc
	Gsk3b^tm1Jrw/Gsk3b^tm1Jrw
	Gsk3b^tm1Grc/Gsk3b^tm1Jrw
	Gsk3b^tm1.1Ypc/Gsk3b^tm1.1Ypc Tg(Pitx2-cre)1Ych/0 (conditional)
	Gsk3b^tm1.1Ypc/Gsk3b^tm1.1Ypc Osr2^tm2(cre)Jian/Osr2⁺ (conditional)	*

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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