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Symbol
Name
ID

Spp1
secreted phosphoprotein 1
MGI:98389

Phenotype annotations related to cellular

Darker colors indicate more annotations

Human Phenotypes	Increased circulating IgA level	Increased circulating IgG level	Decreased circulating antibody level	Paraproteinemia
Disease(s) Associated with SPP1
multiple myeloma

Mouse Phenotypes		decreased sensitivity to induced cell death	decreased susceptibility to dopaminergic neuron neurotoxicity	renal tubular necrosis	decreased fibroblast chemotaxis	abnormal macrophage chemotaxis	impaired macrophage chemotaxis	abnormal leukocyte migration	abnormal osteoblast physiology
Availability	Mouse Genotype	decreased sensitivity to induced cell death		renal tubular necrosis	decreased fibroblast chemotaxis	abnormal macrophage chemotaxis	impaired macrophage chemotaxis	abnormal leukocyte migration	abnormal osteoblast physiology
	Spp1^tm1Blh/Spp1^tm1Blh
	Spp1^tm1Rit/Spp1^tm1Rit
	Spp1^tm1Blh/Spp1⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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