Symbol Name ID |
Pnp
purine-nucleoside phosphorylase MGI:97365 |
Darker colors indicate more annotations |
Human Phenotypes | Decreased lymphocyte proliferation in response to mitogen |
Abnormality of B cell physiology |
Impaired T cell function |
Disease(s) Associated with PNP | |||
purine nucleoside phosphorylase deficiency |
Mouse Phenotypes | increased cellular sensitivity to gamma-irradiation |
increased thymocyte apoptosis |
decreased B cell proliferation |
abnormal DNA repair |
abnormal mitochondrial physiology |
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Availability | Mouse Genotype | |||||
Pnpbata/Pnpbata | ||||||
Pnptm1Cmr/Pnptm1Cmr |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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