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Symbol Name ID |
Kras
Kirsten rat sarcoma viral oncogene homolog MGI:96680 |
| Darker colors indicate more annotations |
| Human Phenotypes | Decreased lymphocyte apoptosis |
Increased circulating IgA level |
Increased circulating IgG level |
Decreased circulating antibody level |
Increased circulating antibody level |
Paraproteinemia |
| Disease(s) Associated with KRAS | ||||||
| autoimmune lymphoproliferative syndrome type 4 | ||||||
| multiple myeloma |
| Mouse Phenotypes | abnormal fetal cardiomyocyte proliferation |
abnormal intestinal goblet cell morphology |
abnormal colon goblet cell morphology |
increased embryonic tissue cell apoptosis |
increased neuron apoptosis |
increased apoptosis |
increased hepatocyte apoptosis |
increased embryonic neuroepithelium apoptosis |
cellular necrosis |
abnormal cell proliferation |
abnormal fibroblast proliferation |
increased splenocyte proliferation |
increased cell proliferation |
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| Availability | Mouse Genotype | |||||||||||||
| Krastm1Mok/Krastm1Mok | ||||||||||||||
| Krastm1Tyj/Krastm1Tyj | ||||||||||||||
| Krastm4.1Bbd/Krastm4.1Bbd | ||||||||||||||
| Krastm4.1Tyj/Kras+ | ||||||||||||||
| Krastm4Tyj/Krastm4Tyj (conditional) | ||||||||||||||
| Krastm1Bbd/Krastm2Bbd Polr2atm1(cre/ERT2)Bbd/Polr2atm1(cre/ERT2)Bbd (conditional) |
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| Krastm4Tyj/Kras+ Gt(ROSA)26Sortm1(cre/ERT2)Tyj/Gt(ROSA)26Sor+ (conditional) |
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| Krastm1Bbd/Kras+ Tg(CMV-cre)1Cgn/? (conditional) |
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| Krastm1Bbd/Kras+ Tg(CMV-cre/ERT)1Ipc/0 (conditional) |
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| Krastm4Tyj/Kras+ Tg(Fabp1-cre)1Jig/0 (conditional) |
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| Krastm4Tyj/Kras+ Tg(Prm-cre)58Og/0 (conditional) |
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| Krastm4Tyj/Kras+ Meox2tm1(cre)Sor/Meox2+ (conditional) |
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| Krastm4Tyj/Kras+ Krt19tm1(cre/ERT)Ggu/Krt19+ (conditional) |
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| Krastm4Tyj/Kras+ Tg(Mx1-cre)1Cgn/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/21/2024 MGI 6.23 |
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