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Symbol
Name
ID
Mtor
mechanistic target of rapamycin kinase
MGI:1928394
Phenotype annotations related to cellular
Darker colors indicate more annotations

Mouse Phenotypes
cardiac interstitial fibrosis
increased cardiomyocyte apoptosis
abnormal cell morphology
decreased mitochondrial number
dilated mitochondrion
abnormal autophagy
decreased splenocyte apoptosis
decreased B cell proliferation
decreased T cell proliferation
absent inner cell mass proliferation
decreased splenocyte proliferation
abnormal mitochondrial physiology
abnormal translation
Availability Mouse Genotype
MtorGt(OST92090)Lex/MtorGt(OST92090)Lex
Mtortm1Lgm/Mtortm1Lgm
Mtortm1Yam/Mtortm1Yam
Mtortm1.1Gcon/Mtortm1.1Gcon
A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+  (conditional)
Mtortm1.2Koz/Mtortm1.2Koz
Tg(Cd4-cre)1Cwi/0  (conditional)
Mtortm1.2Koz/Mtortm1.2Koz
Tg(ACTA1-cre)79Jme/?  (conditional)
Mtortm1.1Seq/Mtortm1.2Seq
Tg(Nphs2-cre)1Seq/?  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory