About Help FAQ

Symbol
Name
ID

Cxcr4
C-X-C motif chemokine receptor 4
MGI:109563

Phenotype annotations related to cellular

Darker colors indicate more annotations

Human Phenotypes	Decreased circulating IgG level	Monoclonal immunoglobulin M proteinemia	Polyclonal elevation of IgM	Decreased circulating antibody level
Disease(s) Associated with CXCR4	Decreased circulating IgG level	Monoclonal immunoglobulin M proteinemia	Polyclonal elevation of IgM	Decreased circulating antibody level
lymphoplasmacytic lymphoma
WHIM syndrome

Mouse Phenotypes		cardiac interstitial fibrosis	decreased primordial germ cell number	decreased B cell apoptosis	abnormal cell chemotaxis	abnormal leukocyte migration	abnormal muscle precursor cell migration	abnormal primordial germ cell migration
Availability	Mouse Genotype	cardiac interstitial fibrosis	decreased primordial germ cell number	decreased B cell apoptosis	abnormal cell chemotaxis	abnormal leukocyte migration	abnormal muscle precursor cell migration	abnormal primordial germ cell migration
	Cxcr4^tm1Qma/Cxcr4^tm1Qma
	Cxcr4^tm1Tng/Cxcr4^tm1Tng
	Cxcr4^tm1Yzo/Cxcr4^tm1Yzo
	Cxcr4^tm1.1Bala/Cxcr4⁺
	Cxcr4^tm1Yiw/Cxcr4^tm1Yiw Tg(Lck-cre)1Jtak/0 (conditional)
	Cxcr4^tm2Yzo/Cxcr4^tm2Yzo Tg(Myh6-cre)2182Mds/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/14/2024 MGI 6.23