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Symbol
Name
ID
Gclc
glutamate-cysteine ligase, catalytic subunit
MGI:104990
Phenotype annotations related to cellular
Darker colors indicate more annotations

Mouse Phenotypes
abnormal endoplasmic reticulum morphology
abnormal mitochondrial morphology
decreased mitochondrial number
increased embryonic tissue cell apoptosis
decreased cell proliferation
abnormal mitochondrial physiology
oxidative stress
Availability Mouse Genotype
Gclctm1Mwl/Gclctm1Mwl
Gclctm1c(EUCOMM)Wtsi/Gclctm1c(EUCOMM)Wtsi
Tg(Cryaa-cre)10Mlr/0  (conditional)
Gclctm1Tdal/Gclctm1Tdal
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+  (conditional)
Gclctm1c(EUCOMM)Wtsi/Gclc+
Tg(Cryaa-cre)10Mlr/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory