Symbol
Name
ID

Prkdc
protein kinase, DNA activated, catalytic polypeptide
MGI:104779

Phenotype annotations related to cellular

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Mouse Phenotypes

cellular phenotype

increased sensitivity to induced cell death

increased cellular sensitivity to alkylating agents

increased cellular sensitivity to ionizing radiation

increased cellular sensitivity to X-ray irradiation

increased cellular sensitivity to gamma-irradiation

increased cellular sensitivity to ultraviolet irradiation

decreased thymocyte apoptosis

increased small intestinal crypt cell apoptosis

decreased B cell proliferation

decreased T cell proliferation

abnormal DNA repair

Availability

Mouse Genotype

Prkdc^dxnph/Prkdc^dxnph

Prkdc^scid/Prkdc^scid

Prkdc^tm1.1Bpcc/Prkdc^tm1.1Bpcc

Prkdc^tm1Fwa/Prkdc^tm1Fwa

Prkdc^tm1Gcl/Prkdc^tm1Gcl

Prkdc^tm1Get/Prkdc^tm1Get

Prkdc^{Tg(INS-PDE2)5-1Lmb}/?

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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